Given that I am always in contact with Sponge team members if a release close to the submission deadline were to happen I would make a ruling based on how much time remains.
In general we want all submissions to be compatible with the latest release available at the time of the submission deadline. If plugin ‘BananaTrees’ targets 4.1 and 5.0 is the latest, we will not disqualify them unless it is incompatible with the latest. Submissions that target different API versions will only be disqualified if they are not compatible with the latest release.